Our goal at ACS Laboratory is to provide the most accurate qualitative and quantitative testing analyses for our clients in the mushroom industry so that they can offer consumption of the best and most reliable products possible. With the exponential and rapid increase in the common use of magic mushrooms and functional mushroom consumption, cultivation, and decriminalization of illegal strains containing a psychedelic compound over the past decade, comes a class of mycological enthusiasts, and medicinal patients, with standards that are more concerned with being aware and informed of the differences in specifies, as well as chemicals that elicit the specific effect of these compounds. To quantitatively identify these analytes, we provide certificates of analysis for all of our DEA licensed clients' psychedelic mushroom samples so that they can ensure potency and purity.
For our clients testing functional mushrooms we provide testing for purity, in the same way we test cannabis and hemp.
What we test for in Psychedelic Mushrooms from DEA licensed producers:
References
https://secure.sos.state.or.us/oard/
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Rules and Regulations
https://knowthefactsmmj.com/rules-and-regulations/
Our clients include the nation's leading psychedelic and functional mushroom researchers. When analyzing hallucinogenic mushroom samples for potency, we quantitatively measure the following analytes:
Psilocybin
As a prodrug, psilocybin is quickly converted by the body to psilocin when ingested. It is broken down by the liver in a process called dephosphorylation. The resulting compound is called psilocin, which is responsible for the psychedelic effects.
Psilocin
Present in most psychedelic mushrooms together with its phosphorylated counterpart psilocybin.
Harmine
beta-carboline alkaloid
Harmane
beta-carboline alkaloid
Baeocystin
psilocybin’s precursor, analog of psilocybin and found as a minor compound.
Norbaecystin
psilocybin’s precursor and found as a minor compound.
Norpsilocin
psilocin’s precursor, found to be a full agonist of 5-HT2A receptor. More potent than psilocin.
Aeruginascin
one of several compounds found in a single species. It is an indoleamine derivative which occurs naturally within the mushrooms.
4-hydroxy-N,N,N
trimethyltryptamine (4-HO-TMT) - The putative active metabolite of aeruginascin, a naturally occurring tryptamine of "psychedelic mushrooms". This compound is closely related to bufotenidine, the N-trimethyl analogue of serotonin found naturally in toad venom.
In addition to our performing testing for psilocybin (psychedelic or “magic”) mushrooms, we also provide purity analyses for many functional or medicinal mushrooms, including:
Mushroom Testing for Purity and Contaminants includes:
References
https://secure.sos.state.or.us/oard/
displayDivisionRules.action?selectedDivision=1222
Rules and Regulations
https://knowthefactsmmj.com/rules-and-regulations/
We analyze and
test a variety of
We are currently conducting ongoing research on the active ingredients of these functional mushrooms and anticipate being able to share the science with the rest of the mycology community in the near future.
Recently, Oregon introduced the draft rules for hallucinogen tests in their legal psychedelic program to be launched in 2023. The state’s newly created Oregon Psilocybin Services section of the Oregon Health Authority, which is the same regulatory body that governs cannabis in the state, was the agency released the information and it comes after the people of Oregon approved Measure 109 in November of 2020. This legislation gives the state of Oregon up to two years to regulate legal psilocybin mushrooms in Oregon. Additionally, the regulatory language specifies species testing of every harvest lot to ensure the presence of only Psilocybe Cubensis. This includes batch testing for every five pounds of whole mushroom fruit, as opposed to cannabis which is required for every fifteen pounds. The analysis to be performed is mandated to include potency testing, solvent testing (for extracts made with methanol), microbial testing for e Coli bacterium, and heavy metal testing for lead, cadmium, arsenic, and mercury.
For proper
analytical testing
Before inoculating the substrate with mushroom spores to begin planting, the substrate itself must be tested. Then, before harvest, it is essential to analyze the mushroom fruits before harvest. After harvest, another analysis must be conducted. After the extraction process, an analysis is performed for the presence of residual solvents. Finally, after all cultivation and extraction is finished, there must be an analysis of the finished mushroom product, such as a food product or capsules.
In order to
validate the
When selecting a mushroom testing laboratory, there are a number of different factors, accreditations, and testing methodologies that should be taken into account. First and foremost, as required by Drug Enforcement Administration regulations, our laboratory has accreditation from the federal level of government. In addition, we are registered with the DEA, AHCA, and CLIA, and have been awarded 82 Emerald Badges, an inter-laboratory comparison and proficiency test, in 2019 - 2022. As a result of our years of experience operating as a testing lab aiding in the quantitative aspects of analytical testing, ACS is able to disseminate clinical grade results.
To ensure the
most
Additionally, we have invested in a 20,000 square ft facility, and our site has all of the proper laboratory-grade instruments and chemicals to perform high quality hemp testing. Consequently, we are able to employ the most reliable testing methods available, such as high-performance liquid chromatography, clinical mass spectrometry, and ultra-violet spectroscopy with high-performance liquid chromatography(HPLC/MSMS/ HPLCUV), gas chromatography mass spectrometry (GC/MS), and inductively coupled plasma mass spectroscopy (ICP/MS). We have convenient and knowledgeable customer support teams that are consistently available by phone and we are able to offer 3-5 day turnaround time for test results.
The federal
government
Because psilocybin and psilocin are Schedule 1 substances, handling or possessing them without DEA authorization is a federal crime and punishable under law. However, the DEA does afford companies the ability to apply for federal psilocybin registration. Under this regulation, a company can be allowed to conduct any of seven activities, including manufacturing, distribution, reverse distribution, research, import, export, and chemical analyses.
How accurate is mushroom testing?
Potency testing, for psilocybin, psilocin, and quantification for other active compounds and amino acids, is extremely accurate when quantifying a lower dose, as well as in larger dosages, as the measurements can be quantified to 1/10th of 1% and 1/10th of a milligram and measured in parts per billion.
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